| Long name: |
ALEXA FLUOR 647 Conjugated, SRD5A1 Polyclonal Antibody |
| Also known as: |
Anti-SRD5A1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SRD5A1 |
| Specificity: |
This is a highly specific antibody against SRD5A1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SRD5A1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
5a-Reductase 1 is expressed in all portions of the hair follicle, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, 5a-Reductase 1 shows heterogeneity of protein, In addition, In cultured human skin cells, The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, The enzyme exists as two isoforms: type 1, and has different levels of transcriptional and translational expression, and type 2, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids, whereas 5a-Reductase 2 is expressed only in mesenchymal portions, which is expressed mainly in the prostate, which is expressed mainly in the skin, which mediates androgen effects on target tissues, Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SRD5A1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
SRD5A1 |
| Short name: |
SRD5A1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, SRD5A1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11284 |
| Gene: |
SRD5A1 |
More about : SRD5A1 |
| Long gene name: |
steroid 5 alpha-reductase 1 |
| Synonyms gene name: |
alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) , steroid-5-alpha-reductase |
| Synonyms name: |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
| Locus: |
5p15, 31 |
| Discovery year: |
1991-05-21 |
| GenBank acession: |
M32313 |
| Entrez gene record: |
6715 |
| Pubmed identfication: |
1686016 |
| RefSeq identity: |
NM_001047 |
| Havana BLAST/BLAT: |
OTTHUMG00000090456 |