| Long name: |
FITC Conjugated, DERLIN-1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DERLIN-1 |
| Specificity: |
This is a highly specific antibody against DERLIN-1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DERLIN-1 |
| Gene ID number: |
79139 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Derlin proteins are multi-pass membrane proteins localizing to the ER, Derlin-1, Derlins are involved in transferring misfolded proteins from the ER to the cytosol, Derlins may also be important for cell proliferation, In the case of cytomegalovirus infection, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome, Degradation in endoplasmic reticulum proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MGC3067 PRO2577 FLJ13784 DER1 DER-1 derlin-1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DERLIN-1 Conjugated |
| Short name: |
FITC Conjugated, DERLIN-1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DERLIN-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28454 |
| Gene: |
DERL1 |
More about : DERL1 |
| Long gene name: |
derlin 1 |
| Synonyms gene name: |
Der1-like domain family, member 1 |
| Locus: |
8q24, 13 |
| Discovery year: |
2004-11-02 |
| GenBank acession: |
BC002457 |
| Entrez gene record: |
79139 |
| Pubmed identfication: |
12975309 15215855 |
| RefSeq identity: |
NM_024295 |
| Classification: |
Rhomboid family |
| Havana BLAST/BLAT: |
OTTHUMG00000165080 |