| Long name: |
ALEXA FLUOR 350 Conjugated, DERLIN-1 Polyclonal Antibody |
| Also known as: |
Anti-DERLIN-1 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DERLIN-1 |
| Specificity: |
This is a highly specific antibody against DERLIN-1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DERLIN-1 |
| Gene ID Number: |
79139 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Derlin proteins are multi-pass membrane proteins localizing to the ER, Derlin-1, Derlins are involved in transferring misfolded proteins from the ER to the cytosol, Derlins may also be important for cell proliferation, In the case of cytomegalovirus infection, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome, Degradation in endoplasmic reticulum proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
MGC3067 PRO2577 FLJ13784 DER1 DER-1 derlin-1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
DERLIN-1 |
| Short name: |
DERLIN-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, DERLIN-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28454 |
| Gene: |
DERL1 |
More about : DERL1 |
| Long gene name: |
derlin 1 |
| Synonyms gene name: |
Der1-like domain family, member 1 |
| Locus: |
8q24, 13 |
| Discovery year: |
2004-11-02 |
| GenBank acession: |
BC002457 |
| Entrez gene record: |
79139 |
| Pubmed identfication: |
12975309 15215855 |
| RefSeq identity: |
NM_024295 |
| Classification: |
Rhomboid family |
| Havana BLAST/BLAT: |
OTTHUMG00000165080 |