| Long name: |
NSF Primary Polyclonal Antibody |
| Also known as: |
NSF PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NSF |
| Specificity: |
This is a highly specific antibody against NSF |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSF |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Following membrane fusion, Membrane fusion requires interaction among SNARE1 proteins associated with both donor and acceptor membranes (1, N-ethylmaleimide-sensitive factor (NSF), The ATPase activity of NSF induces a conformational change in the Î, a hexameric ATPase, membrane fusion and eventual recycling of the SNARE complex for subsequent membrane fusion (3, the Î, then associates with the Î, ±, ±, ±, -SNAP cytoplasmic adapter protein binds to the SNARE complex, -SNAP/SNARE complex that leads to its dissociation from the membrane, -SNAP/SNARE complex to mediate SNARE disassembly during membrane fusion (3, 2), 4), 4), Several protein-protein interactions are essential to membrane fusion during endocytosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
N ethylmaleimide sensitive factor, N ethylmaleimide sensitive factor like protein, N ethylmaleimide sensitive fusion protein, N ethylmaleimide sensitive fusion protein, N-ethylmaleimide-sensitive fusion protein, NEM sensitive fusion protein, NEM sensitive fusion protein, NEM-sensitive fusion protein, NSF, NSF_HUMAN, SKD 2, SKD2, SKD2, Vesicle fusing ATPase, Vesicle fusing ATPase, Vesicle-fusing ATPase, Vesicular fusion protein NSF, Vesicular fusion protein NSF, Vesicular-fusion protein NSF, N ethylmaleimide sensitive factor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NSF |
| Short name: |
NSF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
N-ethylmaleimide-sensitive factor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATPase activity, NSF and IDBG-55627 and ENSG00000073969 and 101930324, NSF and IDBG-641203 and ENSBTAG00000008442 and 504457, Nsf and IDBG-213066 and ENSMUSG00000034187 and 18195, Plasma membranes, SKD2, coupled, coupled and also this GO :0046872 : metal ion binding, coupled and molecular function this GO :0045026 and plasma membrane fusion and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001921 and positive regulation of receptor recycling and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006813 and potassium ion transport and biological process this GO :0006887 and exocytosis and biological process this GO :0007268 and synaptic transmission and biological process this GO :0015031 and protein transport and biological process this GO :0017075 and syntaxin-1 binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030165 and PDZ domain binding and molecular function this GO :0032403 and protein complex binding and molecular function this GO :0042623 and ATPase activity, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0017075 : syntaxin-1 binding and also this GO :0019901 : protein kinase binding and also this GO :0019905 : syntaxin binding and also this GO :0030165 : PDZ domain binding and also this GO :0032403 : protein complex binding and also this GO :0042623 : ATPase activity, this GO :0005524 : ATP binding, this GO :0017075 : syntaxin-1 binding, this GO :0019901 : protein kinase binding, this GO :0019905 : syntaxin binding, this GO :0030165 : PDZ domain binding, this GO :0032403 : protein complex binding, this GO :0042623 : ATPase activity, this GO :0046872 : metal ion binding, 4905, N-ethylmaleimide-sensitive factor |
| Identity: |
8016 |
| Gene: |
NSF |
More about : NSF |
| Long gene name: |
N-ethylmaleimide sensitive factor, vesicle fusing ATPase |
| Synonyms gene name: |
N-ethylmaleimide-sensitive factor N-ethylmaleimide sensitive factor |
| Synonyms: |
SKD2 SEC18 |
| Synonyms name: |
N-ethylmaleimide-sensitive factor-like protein |
| Locus: |
17q21, 31 |
| Discovery year: |
1996-08-28 |
| Entrez gene record: |
4905 |
| Pubmed identfication: |
1315316 8875895 |
| RefSeq identity: |
NM_006178 |
| Classification: |
AAA ATPases |
| Havana BLAST/BLAT: |
OTTHUMG00000134315 |