| Long name: |
Cy3 Conjugated, SHANK2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHANK2 |
| Specificity: |
This is a highly specific antibody against SHANK2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SHANK2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes, The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s), The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site, Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development, and cell adhesion molecules, receptors, signaling enzymes, SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
CTTNBP1 ProSAP1 SHANK SPANK-3 |
| Properties: |
1 of the SHANK2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SHANK2 Conjugated |
| Short name: |
Conjugated, SHANK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, SHANK2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14295 |
| Gene: |
SHANK2 |
More about : SHANK2 |
| Long gene name: |
SH3 and multiple ankyrin repeat domains 2 |
| Synonyms gene: |
CORTBP1 |
| Synonyms gene name: |
cortactin binding protein 1 |
| Locus: |
11q13, 3-q13, 4 |
| Discovery year: |
2002-02-22 |
| GenBank acession: |
AF141901 |
| Entrez gene record: |
22941 |
| Pubmed identfication: |
10506216 |
| RefSeq identity: |
NM_012309 |
| Classification: |
Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000154615 |