| Long name: |
ALEXA FLUOR 555 Conjugated, SHANK2 Polyclonal Antibody |
| Also known as: |
Anti-SHANK2 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHANK2 |
| Specificity: |
This is a highly specific antibody against SHANK2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHANK2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes, The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s), The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site, Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development, and cell adhesion molecules, receptors, signaling enzymes, SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
CTTNBP1 ProSAP1 SHANK SPANK-3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
SHANK2 |
| Short name: |
SHANK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, SHANK2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14295 |
| Gene: |
SHANK2 |
More about : SHANK2 |
| Long gene name: |
SH3 and multiple ankyrin repeat domains 2 |
| Synonyms gene: |
CORTBP1 |
| Synonyms gene name: |
cortactin binding protein 1 |
| Locus: |
11q13, 3-q13, 4 |
| Discovery year: |
2002-02-22 |
| GenBank acession: |
AF141901 |
| Entrez gene record: |
22941 |
| Pubmed identfication: |
10506216 |
| RefSeq identity: |
NM_012309 |
| Classification: |
Ankyrin repeat domain containing Sterile alpha motif domain containing PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000154615 |