| Long name: |
TCF12/HEB Primary Polyclonal Antibody |
| Also known as: |
TCF12/HEB PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TCF12/HEB |
| Specificity: |
This is a highly specific antibody against TCF12/HEB |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TCF12 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression, IF2 and HEB, Myf-5 and Myf-6 (also designated MRF-4 or herculin), Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes, One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, the E family, which consists of at least three distinct genes: E2A, Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Class B basic helix-loop-helix protein 20, DNA binding protein HTF4, DNA-binding protein HTF4, E box binding protein, E-box-binding protein, HEB, HTF4, HTF4_HUMAN, TCF-12, Tcf12, Transcription factor 12, Transcription factor HTF-4, Transcription factor HTF4, bHLHb20 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TCF12/HEB |
| Short name: |
TCF12/HEB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TCF12/HEB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11623 |
| Gene: |
TCF12 |
More about : TCF12 |
| Long gene name: |
transcription factor 12 |
| Synonyms: |
HEB HTF4 HsT17266 bHLHb20 |
| Synonyms name: |
helix-loop-helix transcription factor 4 |
| Locus: |
15q21, 3 |
| Discovery year: |
1994-06-17 |
| GenBank acession: |
BC050556 |
| Entrez gene record: |
6938 |
| Pubmed identfication: |
1886779 |
| RefSeq identity: |
NM_003205 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132047 |