| Long name: |
Biotin Conjugated, Miz1/ZNF60 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Miz1/ZNF60 |
| Specificity: |
This is a highly specific antibody against Miz1/ZNF60 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Miz1/ZNF60 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A POZ domain Zn finger protein, Expression of Miz-1 induces potent growth arrest function, Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters, Miz-1 interacts with Myc, N-Myc- and L-Myc, The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1, and this latency is reversed by the addition of Myc, apoptosis and transformation, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, but not Max or other Myc partners, designated Miz-1 for Myc-interacting Zn finger protein-1, differentiation, however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression, including Max and Mxi 1, including c-Myc-, is a specific target of Myc-induced gene repression, The Myc family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
MIZ1 pHZ-67 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Miz1/ZNF60 Conjugated |
| Short name: |
Conjugated, Miz1/ZNF60 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Miz1/ZNF60 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12936 |
| Gene: |
ZBTB17 |
More about : ZBTB17 |
| Long gene name: |
zinc finger and BTB domain containing 17 |
| Synonyms gene: |
ZNF151 ZNF60 |
| Synonyms gene name: |
zinc finger protein 151 (pHZ-67) zinc finger protein 60 |
| Locus: |
1p36, 13 |
| Discovery year: |
1994-03-16 |
| GenBank acession: |
U20647 |
| Entrez gene record: |
7709 |
| RefSeq identity: |
NM_003443 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000009377 |