| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Miz1/ZNF60 |
| Specificity: |
This antibody reacts specifically with Miz1/ZNF60 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Miz1/ZNF60 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A POZ domain Zn finger protein, Expression of Miz-1 induces potent growth arrest function, Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters, Miz-1 interacts with Myc, N-Myc- and L-Myc, The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1, and this latency is reversed by the addition of Myc, apoptosis and transformation, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, but not Max or other Myc partners, designated Miz-1 for Myc-interacting Zn finger protein-1, differentiation, however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression, including Max and Mxi 1, including c-Myc-, is a specific target of Myc-induced gene repression, The Myc family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MIZ1 pHZ-67 |
| Also known as: |
Miz1/ZNF60 Polyclonal Antibody |
| Other name: |
Anti-Miz1/ZNF60 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Miz1/ZNF60 |
| Short name: |
Anti-Miz1/ZNF60 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Miz1/ZNF60 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12936 |
| Gene: |
ZBTB17 |
More about : ZBTB17 |
| Long gene name: |
zinc finger and BTB domain containing 17 |
| Synonyms gene: |
ZNF151 ZNF60 |
| Synonyms gene name: |
zinc finger protein 151 (pHZ-67) zinc finger protein 60 |
| Locus: |
1p36, 13 |
| Discovery year: |
1994-03-16 |
| GenBank acession: |
U20647 |
| Entrez gene record: |
7709 |
| RefSeq identity: |
NM_003443 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000009377 |