| Long name: |
ALEXA FLUOR 594 Conjugated, Lubricin/SZP Polyclonal Antibody |
| Also known as: |
Anti-Lubricin/SZP PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Lubricin/SZP |
| Specificity: |
This is a highly specific antibody against Lubricin/SZP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lubricin/SZP |
| Gene ID Number: |
6401 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule, Defects in the gene encoding for lubricin can cause Jakobs syndrome, It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage, Lubricin inhibits synovial cell adhesion to the cartilage surface, Lubricin is highly expressed in cartilage, Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), also designated proteoglycan-4 or megakaryocyte stimulating factor, but also prevents the deposition of proteins from synovial fluid onto cartilage, is important for boundary lubrication within articulating joints, liver and synovial tissue, Lubricin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
JCAP SZP MSF HAPO bG174L6, 2 FLJ32635 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Lubricin/SZP |
| Short name: |
Lubricin/SZP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Lubricin/SZP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9364 |
| Gene: |
PRG4 |
More about : PRG4 |
| Long gene name: |
proteoglycan 4 |
| Synonyms gene: |
CACP |
| Synonyms gene name: |
(megakaryocyte stimulating factor, arthropathy, articular superficial zone protein, camptodactyly, coxa vara, pericarditis syndrome) , proteoglycan 4 |
| Synonyms name: |
arthropathy, coxa vara, lubricin megakaryocyte stimulating factor articular superficial zone protein Jacobs camptodactyly-arthropathy-pericarditis syndrome camptodactyly, pericarditis syndrome bG174L6, 2 (MSF: megakaryocyte stimulating factor ) |
| Locus: |
1q31, 1 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
U70136 |
| Entrez gene record: |
10216 |
| Pubmed identfication: |
10545950 9920774 |
| RefSeq identity: |
NM_005807 |
| Havana BLAST/BLAT: |
OTTHUMG00000035574 |