| Long name: |
SorLA Primary Polyclonal Antibody |
| Also known as: |
SorLA PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SorLA |
| Specificity: |
This is a highly specific antibody against SorLA |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SorLA |
| Gene ID number: |
79845 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Endogenous sorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function, It can also bind to RAP, It is expressed mainly in brain (cerebral cortex, SorLA, SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase, SorLa is a multifunctional endocytis receptor important in lipoprotein and protease uptake, The N-terminal propeptide, a single transmembrane receptor, also known as Sorting protein-related receptor containing LDLR class A (SorLA), binds LDL (the main cholesterol-carrying lipoprotein of plasma) and transports it into cells by endocytosis, but can also be found in liver, can be cleaved by furin or homologous proteases, cerebellum and the occipital pole), is a Type I membrane protein that may be involved in cell-cell interaction, kidney, receptor-associated protein, spinal cord, testis and pancreas, which is removed, Sortilin-related receptor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FLJ21930, FLJ39258, LDLR relative with 11 ligand binding repeats, LDLR relative with 11 ligand-binding repeats, LR 11, LR11, LRP 9, LRP9, Low density lipoprotein receptor relative with 11 ligand binding repeats, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, Mosaic protein LR11, SORL 1, SORL1, SORL_HUMAN, SorLA, SorLA 1, SorLA-1, Sortilin related receptor, Sortilin related receptor LDLR class A repeats containing, Sortilin-related receptor, Sorting protein related receptor containing LDLR class A repeats, Sorting protein-related receptor containing LDLR class A repeats, gp250, C11orf32 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SorLA |
| Short name: |
SorLA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SorLA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11185 |
| Gene: |
SORL1 |
More about : SORL1 |
| Long gene name: |
sortilin related receptor 1 |
| Synonyms gene: |
C11orf32 |
| Synonyms gene name: |
L(DLR class) A repeats-containing , chromosome 11 open reading frame 32 sortilin-related receptor |
| Synonyms: |
gp250 LR11 LRP9 SorLA SorLA-1 |
| Synonyms name: |
LDLR relative with 11 ligand-binding repeats |
| Locus: |
11q24, 1 |
| Discovery year: |
1996-12-27 |
| GenBank acession: |
Y08110 |
| Entrez gene record: |
6653 |
| Pubmed identfication: |
9157966 8940146 |
| RefSeq identity: |
NM_003105 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166057 |