| Long name: |
Biotin Conjugated, PCDH8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PCDH8 |
| Specificity: |
This is a highly specific antibody against PCDH8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
40-90/1070 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PCDH8 |
| Gene ID number: |
5100 |
| Swiss Prot: |
O95206 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway, In hippocampal neurons, May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity), may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity), Calcium-dependent cell-adhesion protein (By similarity) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PAPC ARCADLIN |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PCDH8 Conjugated |
| Short name: |
Conjugated, PCDH8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, protocadherin 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARCADLIN and PAPC, Cell surfaces, PCDH8 and IDBG-36060 and ENSG00000136099 and 5100, PCDH8 and IDBG-628623 and ENSBTAG00000018179 and 513346, Pcdh8 and IDBG-183100 and ENSMUSG00000036422 and 18530, calcium ion binding, this GO :0001756 and somitogenesis and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007268 and synaptic transmission and biological process this GO :0016020 and membrane and cellular component this GO :0016331 and morphogenesis of embryonic epithelium and biological process this GO :0030054 and cell junction and cellular component this GO :0030425 and dendrite and cellular component this GO :0042734 and presynaptic membrane and cellular component this GO :0045211 and postsynaptic membrane and cellular component, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding, protocadherin 8 |
| Identity: |
8660 |
| Gene: |
PCDH8 |
More about : PCDH8 |
| Long gene name: |
protocadherin 8 |
| Locus: |
13q14, 3 |
| Discovery year: |
1998-04-21 |
| GenBank acession: |
AF061573 |
| Entrez gene record: |
5100 |
| Pubmed identfication: |
9787079 9315676 |
| RefSeq identity: |
NM_002590 |
| Classification: |
Non-clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000016979 |