| Long name: |
Biotin Conjugated, LSAMP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LSAMP |
| Specificity: |
This is a highly specific antibody against LSAMP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human LSAMP |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In addition, It is a highly conserved protein between rodents and humans (99% sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways, It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules, LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor, LSAMP may function as a tumor suppressor in renal carcinomas, This suggests that LSAMP plays an important role in the development and function of the limbic system, LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LAMP IGLON3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LSAMP Conjugated |
| Short name: |
Conjugated, LSAMP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, limbic system-associated membrane protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IGLON3 and LAMP, LSAMP and IDBG-50984 and ENSG00000185565 and 4045, Lsamp and IDBG-160888 and ENSMUSG00000061080 and 268890, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0035641 and locomotory exploration behavior and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, limbic system-associated membrane protein |
| Identity: |
6705 |
| Gene: |
LSAMP |
More about : LSAMP |
| Long gene name: |
limbic system-associated membrane protein |
| Synonyms name: |
IgLON family member 3 |
| Locus: |
3q13, 31 |
| Discovery year: |
1998-06-16 |
| GenBank acession: |
U41901 |
| Entrez gene record: |
4045 |
| Pubmed identfication: |
9615236 |
| RefSeq identity: |
NM_002338 |
| Classification: |
I-set domain containing IgLON cell adhesion molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000159308 |