| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LSAMP |
| Specificity: |
This antibody reacts specifically with LSAMP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LSAMP |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In addition, It is a highly conserved protein between rodents and humans (99% sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways, It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules, LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor, LSAMP may function as a tumor suppressor in renal carcinomas, This suggests that LSAMP plays an important role in the development and function of the limbic system, LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAMP IGLON3 |
| Also known as: |
LSAMP Polyclonal Antibody |
| Other name: |
Anti-LSAMP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LSAMP |
| Short name: |
Anti-LSAMP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-limbic system-associated membrane protein (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
IGLON3 and LAMP, LSAMP and IDBG-50984 and ENSG00000185565 and 4045, Lsamp and IDBG-160888 and ENSMUSG00000061080 and 268890, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0035641 and locomotory exploration behavior and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, limbic system-associated membrane protein |
| Identity: |
6705 |
| Gene: |
LSAMP |
More about : LSAMP |
| Long gene name: |
limbic system-associated membrane protein |
| Synonyms name: |
IgLON family member 3 |
| Locus: |
3q13, 31 |
| Discovery year: |
1998-06-16 |
| GenBank acession: |
U41901 |
| Entrez gene record: |
4045 |
| Pubmed identfication: |
9615236 |
| RefSeq identity: |
NM_002338 |
| Classification: |
I-set domain containing IgLON cell adhesion molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000159308 |