| Long name: |
ALEXA FLUOR 488 Conjugated, Junctophilin 3 Polyclonal Antibody |
| Also known as: |
Anti-Junctophilin 3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Junctophilin 3 |
| Specificity: |
This is a highly specific antibody against Junctophilin 3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Junctophilin 3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
-2 and -3, Junctophilin-1 is predominantly expressed in skeletal muscle, Junctophilin-2 is expressed in heart and skeletal muscle, Junctophilin-3 is expressed in brain, Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients, The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder, The three subtypes in this family are Junctophilin-1, as well as an ER/SR membrane spanning hydrophobic C-terminal segment, but is also expressed at low levels in heart, Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
JP-3 CAGL237 HDL2 JP3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Junctophilin 3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Junctophilin 3 |
| Short name: |
Junctophilin 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Junctophilin 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14203 |
| Gene: |
JPH3 |
More about : JPH3 |
| Long gene name: |
junctophilin 3 |
| Synonyms gene: |
TNRC22 |
| Synonyms gene name: |
trinucleotide repeat containing 22 |
| Locus: |
16q24, 2 |
| Discovery year: |
2000-12-08 |
| GenBank acession: |
AB042636 |
| Entrez gene record: |
57338 |
| Pubmed identfication: |
10949023 10891348 |
| Classification: |
Trinucleotide repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000137656 |