| Long name: |
ALEXA FLUOR 350 Conjugated, CDH18 Polyclonal Antibody |
| Also known as: |
Anti-CDH18 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CDH18 |
| Specificity: |
This is a highly specific antibody against CDH18 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDH18 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CDH14 (cadherin 14), CDH24 or CDH14L, EY-cadherin, EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), EY-cadherin is thought to be involved in axon guidance and outgrowth, One of several members of the cadherin superfamily, Specifically, The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, also known as CDH18 (cadherin 18), as well as synaptic adhesion within the CNS, but lacks the HAV cell adhesion sequence that is specific to type I cadherins, implicating EY-cadherin as a potential tumor suppressor, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains, where it plays a role in cell-cell binding events, The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
CDH14 EY-CADHERIN |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
CDH18 |
| Short name: |
CDH18 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, classification 2 (Antibody to), cadherin 18 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDH14 and CDH14L and CDH24, CDH18 and IDBG-13642 and ENSG00000145526 and 1016, CDH18 and IDBG-631065 and ENSBTAG00000037844 and 512080, Cdh18 and IDBG-130778 and ENSMUSG00000040420 and 320865, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045216 and cell-cell junction organization and biological process, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding, type 2, cadherin 18 |
| Identity: |
1757 |
| Gene: |
CDH18 |
More about : CDH18 |
| Long gene name: |
cadherin 18 |
| Synonyms gene name: |
cadherin 18, type 2 |
| Locus: |
5p14, 3 |
| Discovery year: |
1997-06-25 |
| GenBank acession: |
U59325 |
| Entrez gene record: |
1016 |
| Pubmed identfication: |
9030594 10191097 |
| RefSeq identity: |
NM_004934 |
| Classification: |
Type II classical cadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000090578 |