| Long name: |
PSCDBP/CYTIP Primary Polyclonal Antibody |
| Also known as: |
PSCDBP/CYTIP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PSCDBP/CYTIP |
| Specificity: |
This is a highly specific antibody against PSCDBP/CYTIP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSCDBP/CYTIP |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Additionally, After membrane translocation, CYTIP associates with SNX27 (sorting nexin 27) and helps to coordinate trafficking and signaling complexes, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester, CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain, CYTIP is able to sequester it to the cytoplasm, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane, Expressed primarily in hematopoetic cells, Through its ability to bind cytohesin-1, Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway, CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CASP, CYBR, CYTHIP, CYTIP_HUMAN, Cbp HE, Cytip, Cytohesin binder and regulator, Cytohesin-associated scaffolding protein, Cytohesin-binding protein HE, Cytohesin-interacting protein, HE antibody Pleckstrin Homology Sec7 and Coiled-Coil Domains Binding Protein, Pleckstrin homology Sec7 and coiled-coil domains-binding protein, B31 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PSCDBP/CYTIP |
| Short name: |
PSCDBP/CYTIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PSCDBP/cytohesin 1 interacting protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
B3-1 and CASP and CYBR and CYTHIP and HE and PSCDBP, CYTIP and IDBG-641611 and ENSBTAG00000008329 and 540450, CYTIP and IDBG-72874 and ENSG00000115165 and 9595, Cytip and IDBG-171958 and ENSMUSG00000026832 and 227929, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005938 and cell cortex and cellular component this GO :0030155 and regulation of cell adhesion and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, cytohesin 1 interacting protein |
| Identity: |
9506 |
| Gene: |
CYTIP |
More about : CYTIP |
| Long gene name: |
cytohesin 1 interacting protein |
| Synonyms gene: |
PSCDBP |
| Synonyms gene name: |
Sec7 and coiled-coil domains, binding protein , pleckstrin homology |
| Synonyms: |
B3-1 HE CYBR CASP CYTHIP |
| Synonyms name: |
cytohesin binding protein HE cytohesin binder and regulator |
| Locus: |
2q24, 1 |
| Discovery year: |
1999-07-19 |
| GenBank acession: |
L06633 |
| Entrez gene record: |
9595 |
| Pubmed identfication: |
18926288 10343115 11867758 20530790 21562043 |
| RefSeq identity: |
NM_004288 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000154551 |