| Long name: |
Biotin Conjugated, OTOA/DFNB22 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OTOA/DFNB22 |
| Specificity: |
This is a highly specific antibody against OTOA/DFNB22 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human OTOA/DFNB22 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CT108 or DFNB22, Existing as three alternatively spliced isoforms, Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells, Sensorineural deafness results from damage to the neural receptors of the inner ear, also known as OTOA, is a 1, otoancorin is encoded by a gene located on human chromosome 16p12, otoancorin is suggested to act as an adhesion molecule, the nerve pathways to the brain or the area of the brain that receives sound information, which is a form of sensorineural hearing loss, 153 amino acid protein belonging to the stereocilin family, 2, Otoancorin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CT108 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OTOA/DFNB22 Conjugated |
| Short name: |
Conjugated, OTOA/DFNB22 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, OTOA/DFNB22 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16378 |
| Gene: |
OTOA |
More about : OTOA |
| Long gene name: |
otoancorin |
| Synonyms gene: |
DFNB22 |
| Synonyms gene name: |
autosomal recessive 22 , deafness |
| Synonyms name: |
cancer/testis antigen 108 |
| Locus: |
16p12, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AK057335 |
| Entrez gene record: |
146183 |
| Pubmed identfication: |
11972037 19088187 |
| Classification: |
Deafness associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000090721 |