| Long name: |
ALEXA FLUOR 488 Conjugated, OTOA/DFNB22 Polyclonal Antibody |
| Also known as: |
Anti-OTOA/DFNB22 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OTOA/DFNB22 |
| Specificity: |
This is a highly specific antibody against OTOA/DFNB22 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTOA/DFNB22 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CT108 or DFNB22, Existing as three alternatively spliced isoforms, Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells, Sensorineural deafness results from damage to the neural receptors of the inner ear, also known as OTOA, is a 1, otoancorin is encoded by a gene located on human chromosome 16p12, otoancorin is suggested to act as an adhesion molecule, the nerve pathways to the brain or the area of the brain that receives sound information, which is a form of sensorineural hearing loss, 153 amino acid protein belonging to the stereocilin family, 2, Otoancorin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CT108 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the OTOA/DFNB22 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
OTOA/DFNB22 |
| Short name: |
OTOA/DFNB22 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, OTOA/DFNB22 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16378 |
| Gene: |
OTOA |
More about : OTOA |
| Long gene name: |
otoancorin |
| Synonyms gene: |
DFNB22 |
| Synonyms gene name: |
autosomal recessive 22 , deafness |
| Synonyms name: |
cancer/testis antigen 108 |
| Locus: |
16p12, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AK057335 |
| Entrez gene record: |
146183 |
| Pubmed identfication: |
11972037 19088187 |
| Classification: |
Deafness associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000090721 |