| Long name: |
FITC Conjugated, NTN3/Netrin-3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NTN3/Netrin-3 |
| Specificity: |
This is a highly specific antibody against NTN3/Netrin-3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NTN3/Netrin-3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
During peripheral nerve development, In axonal cells, In humans, Neogenin serves as the primary guidance receptor for netrin-3, Neogenin serves as the primary guidance receptor for netrin-3, Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity, Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, and, by the netrin gradient, high netrin-3 expression has been detected in mesenchymal cells, like netrin-1, rather than attracted, sensory ganglia and muscles, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection, the gene encoding for the netrin-3 protein is localized to chromosome 16p13, they can either attract or repel commissural axons at a distance, 3, Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NTN3/Netrin-3 Conjugated |
| Short name: |
FITC Conjugated, NTN3/Netrin-3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NTN3/Netrin-3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8030 |
| Gene: |
NTN3 |
More about : NTN3 |
| Long gene name: |
netrin 3 |
| Synonyms gene: |
NTN2L |
| Synonyms gene name: |
netrin 2 (chicken)-like netrin 2-like (chicken) |
| Synonyms name: |
Netrin-3 |
| Locus: |
16p13, 3 |
| Discovery year: |
1997-02-05 |
| GenBank acession: |
U86759 |
| Entrez gene record: |
4917 |
| Pubmed identfication: |
9143507 10366627 |
| RefSeq identity: |
NM_006181 |
| Classification: |
Netrins |
| Havana BLAST/BLAT: |
OTTHUMG00000128867 |