| Long name: |
Cy7 Conjugated, HAS3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HAS3 |
| Specificity: |
This is a highly specific antibody against HAS3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HAS3 |
| Gene ID number: |
3038 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both HAS1 and HAS2 synthesize high molecular-weight HA, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins, HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis, HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults, IFN-g markedly upregulates HAS3 mRNA, Specifically, The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, The extracellular matrix in most vertebrates express HA, The human HAS3 gene maps to chromosome 16q22, The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix, suggesting distinct functional roles of the three proteins, whereas HAS3 produces lower molecular weight HA, whereas TGF Beta downregulates HAS3 transcript levels, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1, 1, 3 and b-1, 4 glycosidic bonds, HAS1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
HAS3 Conjugated |
| Short name: |
Conjugated, HAS3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, HAS3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4820 |
| Gene: |
HAS3 |
More about : HAS3 |
| Long gene name: |
hyaluronan synthase 3 |
| Locus: |
16q22, 1 |
| Discovery year: |
1996-10-18 |
| GenBank acession: |
BC021853 |
| Entrez gene record: |
3038 |
| Pubmed identfication: |
9169154 9083017 |
| RefSeq identity: |
NM_138612 |
| Classification: |
Glycosyltransferase family 2 |
| Havana BLAST/BLAT: |
OTTHUMG00000137562 |