| Catalog number: | bs-10463R-A488 |
|---|---|
| Price: | 500 € |
| Supplier: | acr |
| Product name: | HEXB chain A Antibody, ALEXA FLUOR 488 |
| Quantity: | 0,1 mg |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, HEXB chain A Polyclonal Antibody |
|---|---|
| Also known as: | Anti-HEXB chain A PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | HEXB chain A |
| Specificity: | This is a highly specific antibody against HEXB chain A |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEXB chain A |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II), Beta-hexosaminidase is composed of two subunits, Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases, Jul 2008], Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses, [provided by RefSeq, alpha and beta, and other molecules containing terminal N-acetyl hexosamines, catalyzes the degradation of the ganglioside GM2, together with the cofactor GM2 activator protein, which are encoded by separate genes, Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the HEXB chain A Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | HEXB chain A |
| Short name: | HEXB chain A Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, HEXB epitope A (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4879 |
| Gene: | HEXB | More about : HEXB |
| Long gene name: | hexosaminidase subunit beta |
| Synonyms gene name: | hexosaminidase B (beta polypeptide) |
| Synonyms name: | beta-hexosaminidase subunit beta |
| Locus: | 5q13, 3 |
| Discovery year: | 2001-06-22 |
| GenBank acession: | M13519 |
| Entrez gene record: | 3074 |
| Pubmed identfication: | 2579389 3013851 |
| RefSeq identity: | NM_000521 |
| Havana BLAST/BLAT: | OTTHUMG00000102057 |
| Locus Specific Databases: | HEXB Locus Database |
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