Long name: |
Cy3 Conjugated, SynGAP (Ser836) Polyclonal Antibody |
Category: |
Conjugated Primary Antibodies |
Conjugation: |
cy3 conjugation kit |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
SynGAP Ser836 |
Specificity: |
This is a highly specific antibody against SynGAP Ser836 |
Modification: |
Phosphorylation |
Modification site: |
Ser836 |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Source: |
KLH conjugated synthetic hosphopeptide derived from human SynGAP around the phosphorylation site of Ser836 |
Gene ID number: |
8831 |
Tested applications: |
IF(IHC-P) |
Recommended dilutions: |
IF(IHC-P)(1:50-200) |
Crossreactivity: |
Mouse, Rat, Human |
Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Antigen background: |
It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors, Its activity is inhibited by phosphorylation by CaMKII, SynGAP (for synaptic GTPase activating protein), SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins, SynGAP may be involved in the regulation of BDNF as well as Ras signaling, a novel synaptic RasGAP, are involved in the organization of synaptic structure, hippocampus and olfactory bulb, is a brain-specific protein abundant in the cortex, which are known to bind to and cluster various membrane proteins, which could result in the activation of the MAP kinase pathway, The PSD-95/SAP 90 family of proteins |
Purification method: |
This antibody was purified via Protein A |
Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
Excitation Emission: |
512, 550nm/570, 615nm |
Synonyms: |
DKFZp761G1421, KIAA1938, MRD5, Neuronal RasGAP, OTTHUMP00000064825, RASA 1, RASA 5, RASA1, RASA5, Ras GTPase activating protein SynGAP, Ras GTPase-activating protein SynGAP, SYGP1_HUMAN, SYNGAP 1, SYNGAP1, SynGAP phospho Ser836, Synaptic Ras GAP 1, Synaptic Ras GTPase activating protein 1, Synaptic Ras GTPase activating protein 1 homolog, Synaptic Ras GTPase activating protein 135kDa, Synaptic Ras GTPase-activating protein 1, Synaptic Ras-GAP 1, p-RASA1Ser836, p-SynGAP Ser836, p135 SynGAP, synaptic Ras GTPase activating protein, SynGAP phospho S836 |
Properties: |
1 of the SynGAP (Ser836) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
Gene target: |
SynGAP (Ser836) Conjugated |
Short name: |
Conjugated, SynGAP (Ser836) Antibody |
Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
Label: |
Cy3 |
Alternative name: |
cyanine 3 coupled, SynGAP (Ser836) (Antibody to) |
Alternative technique: |
antibodies |