Long name: |
ALEXA FLUOR 350 Conjugated, SynGAP (Ser836) Polyclonal Antibody |
Also known as: |
Anti-SynGAP Ser836 PAb ALEXA FLUOR 350 |
Category: |
Conjugated Primary Antibodies |
Conjugated with: |
350, ALEXA FLUOR® |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
SynGAP Ser836 |
Specificity: |
This is a highly specific antibody against SynGAP Ser836 |
Modification: |
Phosphorylation |
Modification Site: |
Ser836 |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Source: |
KLH conjugated synthetic hosphopeptide derived from human SynGAP around the phosphorylation site of Ser836 |
Gene ID Number: |
8831 |
Tested applications: |
IF(IHC-P) |
Recommended dilutions: |
IF(IHC-P)(1:50-200) |
Crossreactivity: |
Mouse, Rat, Human |
Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Background of the antigen: |
It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors, Its activity is inhibited by phosphorylation by CaMKII, SynGAP (for synaptic GTPase activating protein), SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins, SynGAP may be involved in the regulation of BDNF as well as Ras signaling, a novel synaptic RasGAP, are involved in the organization of synaptic structure, hippocampus and olfactory bulb, is a brain-specific protein abundant in the cortex, which are known to bind to and cluster various membrane proteins, which could result in the activation of the MAP kinase pathway, The PSD-95/SAP 90 family of proteins |
Purification: |
Purified by Protein A |
Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
Excitation emission: |
343nm/442nm |
Synonyms: |
DKFZp761G1421, KIAA1938, MRD5, Neuronal RasGAP, OTTHUMP00000064825, RASA 1, RASA 5, RASA1, RASA5, Ras GTPase activating protein SynGAP, Ras GTPase-activating protein SynGAP, SYGP1_HUMAN, SYNGAP 1, SYNGAP1, SynGAP phospho Ser836, Synaptic Ras GAP 1, Synaptic Ras GTPase activating protein 1, Synaptic Ras GTPase activating protein 1 homolog, Synaptic Ras GTPase activating protein 135kDa, Synaptic Ras GTPase-activating protein 1, Synaptic Ras-GAP 1, p-RASA1Ser836, p-SynGAP Ser836, p135 SynGAP, synaptic Ras GTPase activating protein, SynGAP phospho S836 |
Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
Gene target: |
SynGAP (Ser836) |
Short name: |
SynGAP (Ser836) Antibody |
Technique: |
antibodies against human proteins, antibodies for, Antibody |
Label: |
ALEXA FLUOR 350 |
Alternative name: |
ALEXA FLUOR 350, SynGAP (Ser836) (Antibody to) |
Alternative technique: |
antibodies |