Long name: |
FITC Conjugated, Syntrophin-1+2+3 Polyclonal Antibody |
Category: |
Conjugated Primary Antibodies |
Conjugation: |
Anti-FITC Antibody |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
Syntrophin-1+2+3 |
Specificity: |
This is a highly specific antibody against Syntrophin-1+2+3 |
Modification: |
Unmodified |
Modification site: |
None |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Source: |
KLH conjugated synthetic peptide derived from human Syntrophin-1+2+3 |
Tested applications: |
IF(IHC-P) |
Recommended dilutions: |
IF(IHC-P)(1:50-200) |
Crossreactivity: |
Mouse, Rat, Human |
Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Antigen background: |
Jan 2013], The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1, This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues, This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS), This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes, This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue, [provided by RefSeq, 5, Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex |
Purification method: |
This antibody was purified via Protein A |
Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
Excitation Emission: |
494nm/518nm |
Synonyms: |
59kDa dystrophin-associated protein A1 basic component 2, Beta-1-syntrophin, Beta-2-syntrophin, SNT1, SNT2, SNT3, SNTA1, SNTB1, SNTB1_HUMAN, SNTB2, SNTB2_HUMAN, Syntrophin alpha 1, Syntrophin beta 1, Syntrophin beta 2, Syntrophin-1, Syntrophin-2, Syntrophin-3, alpha-1-syntrophin, SNTA1_HUMAN |
Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
Gene target: |
Syntrophin-1+2+3 Conjugated |
Short name: |
FITC Conjugated, Syntrophin-1+2+3 Antibody |
Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
Label: |
FITC |
Alternative name: |
fluorecein coupled, Syntrophin-1+2+3 (Antibody to) |
Alternative technique: |
antibodies |