| Long name: |
Syntrophin/SNTA1/Syntrophin Alpha1 Antibody |
| Also known as: |
Syntrophin/SNTA1/Syntrophin Alpha1 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Syntrophin/SNTA1/Syntrophin Alpha1 |
| Specificity: |
This is a highly specific antibody against Syntrophin/SNTA1/Syntrophin Alpha1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Syntrophins/SNTA1 |
| Gene ID number: |
6640 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Jan 2013], The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1, This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues, This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS), This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes, This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue, [provided by RefSeq, 5, Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
SNT2, SNT3, SNTA1, SNTB1, SNTB2, Syntrophin alpha 1, Syntrophin beta 1, Syntrophin beta 2, SNT1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Syntrophin/SNTA1/Syntrophin Alpha1 |
| Short name: |
Syntrophin/SNTA1/Syntrophin Alpha1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Syntrophin/SNTA1/Syntrophin Alpha1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11167 |
| Gene: |
SNTA1 |
More about : SNTA1 |
| Long gene name: |
syntrophin alpha 1 |
| Synonyms gene: |
SNT1 |
| Synonyms gene name: |
59kD, acidic component) , alpha 1 (dystrophin-associated protein A1, syntrophin |
| Synonyms: |
TACIP1 LQT12 |
| Synonyms name: |
59kDa, acidic component , pro-TGF-alpha cytoplasmic domain-interacting protein 1 dystrophin-associated protein A1 |
| Locus: |
20q11, 21 |
| Discovery year: |
1994-12-14 |
| GenBank acession: |
U40571 |
| Entrez gene record: |
6640 |
| Pubmed identfication: |
8576247 8612778 |
| RefSeq identity: |
NM_003098 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000032259 |
| Locus Specific Databases: |
SNTA1 database at LOVD-China LRG_332 |