Long name: |
ALEXA FLUOR 594 Conjugated, Syntrophin-1+2+3 Polyclonal Antibody |
Also known as: |
Anti-Syntrophin-1+2+3 PAb ALEXA FLUOR 594 |
Category: |
Conjugated Primary Antibodies |
Conjugated with: |
594, ALEXA FLUOR® |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
Syntrophin-1+2+3 |
Specificity: |
This is a highly specific antibody against Syntrophin-1+2+3 |
Modification: |
Unmodified |
Modification Site: |
None |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Syntrophin-1+2+3 |
Tested applications: |
IF(IHC-P) |
Recommended dilutions: |
IF(IHC-P)(1:50-200) |
Crossreactivity: |
Mouse, Rat, Human |
Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Background of the antigen: |
Jan 2013], The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1, This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues, This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS), This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes, This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue, [provided by RefSeq, 5, Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex |
Purification: |
Purified by Protein A |
Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
Excitation emission: |
590nm/617nm |
Synonyms: |
59kDa dystrophin-associated protein A1 basic component 2, Beta-1-syntrophin, Beta-2-syntrophin, SNT1, SNT2, SNT3, SNTA1, SNTB1, SNTB1_HUMAN, SNTB2, SNTB2_HUMAN, Syntrophin alpha 1, Syntrophin beta 1, Syntrophin beta 2, Syntrophin-1, Syntrophin-2, Syntrophin-3, alpha-1-syntrophin, SNTA1_HUMAN |
Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
Conjugated: |
Alexa conjugate 1 |
Gene target: |
Syntrophin-1+2+3 |
Short name: |
Syntrophin-1+2+3 Antibody |
Technique: |
antibodies against human proteins, antibodies for, Antibody |
Label: |
ALEXA FLUOR 594 |
Alternative name: |
ALEXA FLUOR 594, Syntrophin-1+2+3 (Antibody to) |
Alternative technique: |
antibodies |