| Long name: |
c-Abl(Thr754 + Thr735) Antibody |
| Also known as: |
c-Abl(Thr754 + Thr735) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
c-Abl Thr754 + Thr735 |
| Specificity: |
This is a highly specific antibody against c-Abl Thr754 + Thr735 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr754 + Thr735 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Thr754 |
| Gene ID number: |
25 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase, the c Abl proto oncogene undergoes a (9, 22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22, The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ABL, ABL1_HUMAN, Abelson Murine Leukemia Viral Oncogene Homolog 1, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, p150, v abl, v abl Abelson murine leukemia viral oncogene homolog 1, c-AblThr754/Thr735 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-Abl(Thr754 + Thr735) |
| Short name: |
c-Abl(Thr754 + Thr735) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
c-Abl(Thr754 and Thr735) (Antibody to) |
| Alternative technique: |
antibodies |