| Long name: |
ALEXA FLUOR 594 Conjugated, Factor I heavy chain Polyclonal Antibody |
| Also known as: |
Anti-Factor I heavy chain PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Factor I heavy chain |
| Specificity: |
This is a highly specific antibody against Factor I heavy chain |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement factor I heavy chain |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CR1 or MCP are required for C3b cleavage, Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases, Factor H, Factor I is a serine protease with a high degree of specificity for C3b and C4b, It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, It requires protein cofactors for cleavage of these complement proteins, There are three pathways of complement activation: the classical pathway, and C4bp or CR1 are required for C4b cleavage, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis, lectin pathway and alternative pathway, The complement pathway is an important host defense system that contributes to both innate and acquired immunity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
, AHUS3, C3B/C4B inactivator, C3BINA, C3b INA, C3b inactivator, CFAI_HUMAN, CFI, Complement component I, Complement control protein factor I, Complement factor I, Complement factor I heavy chain, F1, FI, FactorI, Heavy chain of factor I, I factor, KAF, Konglutinogen activating factor, OTTHUMP00000219728, factor I, Factor I heavy chain |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Factor I heavy chain |
| Short name: |
Factor I heavy chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Factor I heavy epitope (Antibody to) |
| Alternative technique: |
antibodies |