| Long name: |
Biotin Conjugated, ODF2/Cenexin1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ODF2/Cenexin1 |
| Specificity: |
This is a highly specific antibody against ODF2/Cenexin1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human ODF2/Cenexin1 |
| Gene ID number: |
4957 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles, Cenexin1 is required for proper localization of Plk1 to the centrosomes, Cenexin1 is required for proper mitotic progression, Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2, ODF2 is a major component of sperm tail outer dense fibers (ODFs), ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail, The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, This centrosomal localization of Plk1 is required for proper microtubule function, and may also modulate sperm motility, depletion of Cenexin1 ultimately leads to chromosome missegregation and apoptosis, that unlike ODF2 is present in several somatic cell types, which have very different functions, Cenexin1 is an isoform of ODF2 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ODF84 CT134 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ODF2/Cenexin1 Conjugated |
| Short name: |
Conjugated, ODF2/Cenexin1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ODF2/Cenexin1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8114 |
| Gene: |
ODF2 |
More about : ODF2 |
| Long gene name: |
outer dense fiber of sperm tails 2 |
| Synonyms gene name: |
outer dense fibre of sperm tails 2 |
| Synonyms name: |
cancer/testis antigen 134 cenexin |
| Locus: |
9q34, 11 |
| Discovery year: |
1998-07-03 |
| GenBank acession: |
AF012549 |
| Entrez gene record: |
4957 |
| Pubmed identfication: |
9045620 10072582 |
| Havana BLAST/BLAT: |
OTTHUMG00000020748 |