| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ODF2/Cenexin1 |
| Specificity: |
This antibody reacts specifically with ODF2/Cenexin1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ODF2/Cenexin1 |
| Gene ID: |
4957 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles, Cenexin1 is required for proper localization of Plk1 to the centrosomes, Cenexin1 is required for proper mitotic progression, Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2, ODF2 is a major component of sperm tail outer dense fibers (ODFs), ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail, The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, This centrosomal localization of Plk1 is required for proper microtubule function, and may also modulate sperm motility, depletion of Cenexin1 ultimately leads to chromosome missegregation and apoptosis, that unlike ODF2 is present in several somatic cell types, which have very different functions, Cenexin1 is an isoform of ODF2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ODF84 CT134 |
| Also known as: |
ODF2/Cenexin1 Polyclonal Antibody |
| Other name: |
Anti-ODF2/Cenexin1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ODF2/Cenexin1 |
| Short name: |
Anti-ODF2/Cenexin1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ODF2/Cenexin1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8114 |
| Gene: |
ODF2 |
More about : ODF2 |
| Long gene name: |
outer dense fiber of sperm tails 2 |
| Synonyms gene name: |
outer dense fibre of sperm tails 2 |
| Synonyms name: |
cancer/testis antigen 134 cenexin |
| Locus: |
9q34, 11 |
| Discovery year: |
1998-07-03 |
| GenBank acession: |
AF012549 |
| Entrez gene record: |
4957 |
| Pubmed identfication: |
9045620 10072582 |
| Havana BLAST/BLAT: |
OTTHUMG00000020748 |