VAV3(Tyr141) Antibody, ALEXA FLUOR 555

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Catalog number: bs-10271R-A555
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: VAV3(Tyr141) Antibody, ALEXA FLUOR 555
Quantity: 100ul
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Long name: ALEXA FLUOR 555 Conjugated, VAV3(Tyr141) Polyclonal Antibody
Also known as: Anti-VAV3 Tyr141 PAb ALEXA FLUOR 555
Category: Conjugated Primary Antibodies
Conjugated with: 555, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: VAV3 Tyr141
Specificity: This is a highly specific antibody against VAV3 Tyr141
Modification: Phosphorylation
Modification Site: Tyr141
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Cytoplasm
Source: KLH conjugated synthetic phosphopeptide derived from human VAV3 around the phosphorylation site of Tyr141
Gene ID Number: 10451
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Encforced Vav3 expression leads to the appearance of multinucleate cells, Following these events, Furthermore, SLP76 and 3BP2, Vav affects IL-2 promotor activity, Vav3, Vav3 expression follows a cell cycle-dependent pattern, and subsequently interacts with 2 adaptor molecules, however, implicating a role for Vav3 in the control of cytokinesis, like Vav (also known as Vav1 or p95Vav), the paths of Vav and Vav3 diverge, undergoes tyrosine phosphorylation downstream of T cell receptor cross-linkage, while Vav3 impacts gene transcription linked to serum response element (SRE), with transient upregulation occuring during mitosis, The Vav family of Rho guanine nucleotide exchange factors (GEFs) orchestrate signaling events following lymphocyte antigen receptor activation
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 553nm/568nm
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 555, Alexa Fluor
Gene target: VAV3(Tyr141)
Short name: VAV3(Tyr141) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 555
Alternative name: ALEXA FLUOR 555, vav 3 guanine nucleotide exchange factor(Tyr141) (Antibody to)
Alternative technique: antibodies
Alternative to gene target: Plasma membranes, VAV3 and IDBG-100649 and ENSG00000134215 and 10451, VAV3 and IDBG-635847 and ENSBTAG00000031575 and 521961, Vav3 and IDBG-188386 and ENSMUSG00000033721 and 57257, metal ion binding, this GO :0001525 and angiogenesis and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005154 and epidermal growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006906 and vesicle fusion and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0016477 and cell migration and biological process this GO :0030031 and cell projection assembly and biological process this GO :0030032 and lamellipodium assembly and biological process this GO :0030168 and platelet activation and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0032314 and regulation of Rac GTPase activity and biological process this GO :0032319 and regulation of Rho GTPase activity and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042493 and response to drug and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043087 and regulation of GTPase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005096 : GTPase activator activity and also this GO :0005154 : epidermal growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0030676 : Rac guanyl-nucleotide exchange factor activity and also this GO :0046872 : metal ion binding, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005096 : GTPase activator activity, this GO :0005154 : epidermal growth factor receptor binding, this GO :0005515 : protein binding, this GO :0030676 : Rac guanyl-nucleotide exchange factor activity, this GO :0046872 : metal ion binding, vav 3 guanine nucleotide exchange factor
Identity: 12659
Gene: VAV3 | More about : VAV3
Long gene name: vav guanine nucleotide exchange factor 3
Synonyms gene name: vav 3 oncogene vav 3 guanine nucleotide exchange factor
Locus: 1p13, 3
Discovery year: 1999-07-07
GenBank acession: AF118886
Entrez gene record: 10451
RefSeq identity: NM_006113
Classification: Rho guanine nucleotide exchange factors Pleckstrin homology domain containing SH2 domain containing
Havana BLAST/BLAT: OTTHUMG00000010995

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