| Long name: |
FITC Conjugated, CMKLR1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CMKLR1 |
| Specificity: |
This is a highly specific antibody against CMKLR1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
175-222/371 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse CMKLR1 |
| Gene ID number: |
14747 |
| Swiss Prot: |
P97468 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Mouse |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Interaction with RARRES2 induces activation of intracellular signaling molecules, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, Positively regulates adipogenesis and adipocyte metabolism, Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity), enhancing of adipogenesis and angionesis, like reduction of immune responses, such as SKY, Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
RVER1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CMKLR1 Conjugated |
| Short name: |
FITC Conjugated, CMKLR1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, chemokine-like receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CHEMERINR and ChemR23 and DEZ and RVER1, CMKLR1 and IDBG-55274 and ENSG00000174600 and 1240, CMLKR1 and IDBG-647886 and ENSBTAG00000022039 and 615411, Cmklr1 and IDBG-191760 and ENSMUSG00000042190 and 14747, Plasma membranes, protein binding, this GO :0001501 and skeletal system development and biological process this GO :0004872 and receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0010759 and positive regulation of macrophage chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0050848 and regulation of calcium-mediated signaling and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, chemokine-like receptor 1 |
| Identity: |
2121 |
| Gene: |
CMKLR1 |
More about : CMKLR1 |
| Long gene name: |
chemerin chemokine-like receptor 1 |
| Synonyms gene name: |
chemokine-like receptor 1 |
| Synonyms name: |
resolvin E1 receptor chemerin receptor |
| Locus: |
12q23, 3 |
| Discovery year: |
1995-11-22 |
| GenBank acession: |
U79526 |
| Entrez gene record: |
1240 |
| Classification: |
Chemerin receptor |
| Havana BLAST/BLAT: |
OTTHUMG00000169576 |