| Long name: |
ALEXA FLUOR 350 Conjugated, CMKLR1 Polyclonal Antibody |
| Also known as: |
Anti-CMKLR1 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CMKLR1 |
| Specificity: |
This is a highly specific antibody against CMKLR1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
175-222/371 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse CMKLR1 |
| Gene ID Number: |
14747 |
| Swiss Prot: |
P97468 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Mouse |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Interaction with RARRES2 induces activation of intracellular signaling molecules, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, Positively regulates adipogenesis and adipocyte metabolism, Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity), enhancing of adipogenesis and angionesis, like reduction of immune responses, such as SKY, Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
RVER1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
CMKLR1 |
| Short name: |
CMKLR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, chemokine-like receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CHEMERINR and ChemR23 and DEZ and RVER1, CMKLR1 and IDBG-55274 and ENSG00000174600 and 1240, CMLKR1 and IDBG-647886 and ENSBTAG00000022039 and 615411, Cmklr1 and IDBG-191760 and ENSMUSG00000042190 and 14747, Plasma membranes, protein binding, this GO :0001501 and skeletal system development and biological process this GO :0004872 and receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0010759 and positive regulation of macrophage chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0050848 and regulation of calcium-mediated signaling and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, chemokine-like receptor 1 |
| Identity: |
2121 |
| Gene: |
CMKLR1 |
More about : CMKLR1 |
| Long gene name: |
chemerin chemokine-like receptor 1 |
| Synonyms gene name: |
chemokine-like receptor 1 |
| Synonyms name: |
resolvin E1 receptor chemerin receptor |
| Locus: |
12q23, 3 |
| Discovery year: |
1995-11-22 |
| GenBank acession: |
U79526 |
| Entrez gene record: |
1240 |
| Classification: |
Chemerin receptor |
| Havana BLAST/BLAT: |
OTTHUMG00000169576 |