| Long name: |
Biotin Conjugated, HRH4/GPCR105 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HRH4/GPCR105 |
| Specificity: |
This is a highly specific antibody against HRH4/GPCR105 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human HRH4/GPCR105 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
H2, H3 and H4, Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors, Its various actions are mediated by histamine receptors H1, and neurons, and trachea, bone marrow, colon, enterochromaffin-like cells, liver, lung, smalll intestine, spleen, testis, thymus, tonsil, Histamine is a ubiquitous messenger molecule released from mast cells, The Histamine H4 receptor has been reported in human blood peripheral leukocytes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
H4R HH4R AXOR35 GPCR105 GPRv53 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HRH4/GPCR105 Conjugated |
| Short name: |
Conjugated, HRH4/GPCR105 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, histamine receptor H4/GPCR105 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HRH4 and IDBG-1754 and ENSG00000134489 and 59340, HRH4 and IDBG-643833 and ENSBTAG00000020467 and 783354, Hrh4 and IDBG-129289 and ENSMUSG00000037346 and 225192, Plasma membranes, histamine receptor activity, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004969 and histamine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0008150 and biological process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0043408 and regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004969 : histamine receptor activity, this GO :0004969 : histamine receptor activity, histamine receptor H4 |
| Identity: |
17383 |
| Gene: |
HRH4 |
More about : HRH4 |
| Long gene name: |
histamine receptor H4 |
| Locus: |
18q11, 2 |
| Discovery year: |
2002-11-26 |
| GenBank acession: |
AF312230 |
| Entrez gene record: |
59340 |
| Pubmed identfication: |
11118334 10973974 |
| Classification: |
Histamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131945 |