| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HRH4/GPCR105 |
| Specificity: |
This antibody reacts specifically with HRH4/GPCR105 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HRH4/GPCR105 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
H2, H3 and H4, Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors, Its various actions are mediated by histamine receptors H1, and neurons, and trachea, bone marrow, colon, enterochromaffin-like cells, liver, lung, smalll intestine, spleen, testis, thymus, tonsil, Histamine is a ubiquitous messenger molecule released from mast cells, The Histamine H4 receptor has been reported in human blood peripheral leukocytes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
H4R HH4R AXOR35 GPCR105 GPRv53 |
| Also known as: |
HRH4/GPCR105 Polyclonal Antibody |
| Other name: |
Anti-HRH4/GPCR105 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HRH4/GPCR105 |
| Short name: |
Anti-HRH4/GPCR105 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-histamine receptor H4/GPCR105 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
HRH4 and IDBG-1754 and ENSG00000134489 and 59340, HRH4 and IDBG-643833 and ENSBTAG00000020467 and 783354, Hrh4 and IDBG-129289 and ENSMUSG00000037346 and 225192, Plasma membranes, histamine receptor activity, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004969 and histamine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0008150 and biological process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0043408 and regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004969 : histamine receptor activity, this GO :0004969 : histamine receptor activity, histamine receptor H4 |
| Identity: |
17383 |
| Gene: |
HRH4 |
More about : HRH4 |
| Long gene name: |
histamine receptor H4 |
| Locus: |
18q11, 2 |
| Discovery year: |
2002-11-26 |
| GenBank acession: |
AF312230 |
| Entrez gene record: |
59340 |
| Pubmed identfication: |
11118334 10973974 |
| Classification: |
Histamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131945 |