| Long name: |
Biotin Conjugated, CXCR1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CXCR1 |
| Specificity: |
This is a highly specific antibody against CXCR1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
208-242/350 |
| Subcellular location: |
Cytoplasm |
| Source: |
, KLH conjugated synthetic peptide derived from human CXCR1Â |
| Gene ID number: |
3577 |
| Swiss Prot: |
P25024 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding of IL-8 to the receptor causes activation of neutrophils, This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity, This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system, which is a powerful neutrophils chemotactic factor, Receptor to interleukin-8 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CKR-1 CDw128a CD181 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CXCR1 Conjugated |
| Short name: |
Conjugated, CXCR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, chemokine (C-X-C motif) receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-C and C-C-CKR-1 and CD128 and CD181 and CDw128a and CKR-1 and CMKAR1 and IL8R1 and IL8RA and IL8RBA, CXCR1 and IDBG-80821 and ENSG00000163464 and 3577, Cxcr1 and IDBG-166431 and ENSMUSG00000048480 and 227288, Plasma membranes, interleukin-8 binding, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004918 and interleukin-8 receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019959 and interleukin-8 binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0038112 and interleukin-8-mediated signaling pathway and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004918 : interleukin-8 receptor activity, this GO :0004918 : interleukin-8 receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0019959 : interleukin-8 binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0019959 : interleukin-8 binding, chemokine (C-X-C motif) receptor 1 |
| Identity: |
6026 |
| Gene: |
CXCR1 |
More about : CXCR1 |
| Long gene name: |
C-X-C motif chemokine receptor 1 |
| Synonyms gene: |
CMKAR1 IL8RA |
| Synonyms gene name: |
alpha chemokine (C-X-C motif) receptor 1 , interleukin 8 receptor |
| Locus: |
2q35 |
| Discovery year: |
1992-11-09 |
| GenBank acession: |
U11870 |
| Entrez gene record: |
3577 |
| Pubmed identfication: |
1303245 1427896 |
| RefSeq identity: |
NM_000634 |
| Classification: |
CD molecules C-X-C motif chemokine receptors Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133108 |