| Alternative name 1: |
Biotin, CDw128a, CXCR1, Clone: NVR1, Mab anti-Human, ), Interleukin 8 Receptor alpha (IL-8R&alpha |
| Alternative name 2: |
Biotin, CDw128a, CXCR1, Clone: NVR1, Mab antibody-Human, ), Interleukin 8 Receptor alpha (IL-8R&alpha |
| Alternative name 3: |
Biotin, CDw128a, CXCR1, Clone: NVR1, Mab antibody-Homo sapiens, ), Interleukin 8 Receptor alpha (IL-8R&alpha |
| Alternative name 4: |
CDw128a CXCR1 Clone: NVR1, anti-Interleukin 8 Receptor alpha IL-8R&alpha |
| Alternative name 5: |
CDw128a CXCR1 Clone: NVR1, Interleukin 8 Receptor alpha IL-8R&alpha |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, 6, Biotin conjugates can be detected by horseradish peroxidase, Homo sapiens sapiens), humans , ssp |
| Conjugation: |
Biotinylated |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
CXCR1, Monoclonal, NVR1, ) CDw128a, Interleukin 8 Receptor alpha (IL-8R&alpha |
| Short name: |
CXCR1, Clone: NVR1, Mouse Monoclonal antibody-, ) CDw128a, Interleukin 8 Receptor alpha (IL-8R&alpha |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Label: |
Biotin |
| Species: |
Mouses, Humans |
| Alternative name: |
CDw128a, Mouse monoclonal (Antibody to)-H, biotinilated, chemokine (C-X-C motif) receptor 1, clonality: NVR1, sapiens, ), Interleukin 8 Receptor a (Interleukin-8R&alpha |
| Alternative technique: |
murine |
| Alternative to gene target: |
C-C and C-C-CKR-1 and CD128 and CD181 and CDw128a and CKR-1 and CMKAR1 and IL8R1 and IL8RA and IL8RBA, CXCR1 and IDBG-80821 and ENSG00000163464 and 3577, Cxcr1 and IDBG-166431 and ENSMUSG00000048480 and 227288, Plasma membranes, interleukin-8 binding, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004918 and interleukin-8 receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019959 and interleukin-8 binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0038112 and interleukin-8-mediated signaling pathway and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004918 : interleukin-8 receptor activity, this GO :0004918 : interleukin-8 receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0019959 : interleukin-8 binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0019959 : interleukin-8 binding, chemokine (C-X-C motif) receptor 1 |
| Identity: |
6026 |
| Gene: |
CXCR1 |
More about : CXCR1 |
| Long gene name: |
C-X-C motif chemokine receptor 1 |
| Synonyms gene: |
CMKAR1 IL8RA |
| Synonyms gene name: |
alpha chemokine (C-X-C motif) receptor 1 , interleukin 8 receptor |
| Synonyms: |
CKR-1 CDw128a CD181 |
| Locus: |
2q35 |
| Discovery year: |
1992-11-09 |
| GenBank acession: |
U11870 |
| Entrez gene record: |
3577 |
| Pubmed identfication: |
1303245 1427896 |
| RefSeq identity: |
NM_000634 |
| Classification: |
CD molecules C-X-C motif chemokine receptors Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133108 |