| Long name: |
ALEXA FLUOR 488 Conjugated, CXCR1 Polyclonal Antibody |
| Also known as: |
Anti-CXCR1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CXCR1 |
| Specificity: |
This is a highly specific antibody against CXCR1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
208-242/350 |
| Subcellular location: |
Cytoplasm |
| Source: |
, This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CXCR1Â |
| Gene ID Number: |
3577 |
| Swiss Prot: |
P25024 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binding of IL-8 to the receptor causes activation of neutrophils, This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity, This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system, which is a powerful neutrophils chemotactic factor, Receptor to interleukin-8 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CKR-1 CDw128a CD181 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CXCR1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CXCR1 |
| Short name: |
CXCR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, chemokine (C-X-C motif) receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-C and C-C-CKR-1 and CD128 and CD181 and CDw128a and CKR-1 and CMKAR1 and IL8R1 and IL8RA and IL8RBA, CXCR1 and IDBG-80821 and ENSG00000163464 and 3577, Cxcr1 and IDBG-166431 and ENSMUSG00000048480 and 227288, Plasma membranes, interleukin-8 binding, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004918 and interleukin-8 receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019959 and interleukin-8 binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0038112 and interleukin-8-mediated signaling pathway and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004918 : interleukin-8 receptor activity, this GO :0004918 : interleukin-8 receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0019959 : interleukin-8 binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0019959 : interleukin-8 binding, chemokine (C-X-C motif) receptor 1 |
| Identity: |
6026 |
| Gene: |
CXCR1 |
More about : CXCR1 |
| Long gene name: |
C-X-C motif chemokine receptor 1 |
| Synonyms gene: |
CMKAR1 IL8RA |
| Synonyms gene name: |
alpha chemokine (C-X-C motif) receptor 1 , interleukin 8 receptor |
| Locus: |
2q35 |
| Discovery year: |
1992-11-09 |
| GenBank acession: |
U11870 |
| Entrez gene record: |
3577 |
| Pubmed identfication: |
1303245 1427896 |
| RefSeq identity: |
NM_000634 |
| Classification: |
CD molecules C-X-C motif chemokine receptors Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133108 |