| Long name: |
CXCR1 Primary Polyclonal Antibody |
| Also known as: |
CXCR1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CXCR1 |
| Specificity: |
This is a highly specific antibody against CXCR1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
208-242/350 |
| Subcellular location: |
Cytoplasm |
| Source: |
, This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CXCR1Â |
| Gene ID number: |
3577 |
| Swiss Prot: |
P25024 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binding of IL-8 to the receptor causes activation of neutrophils, This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity, This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system, which is a powerful neutrophils chemotactic factor, Receptor to interleukin-8 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-C-CKR-1, C-X-C chemokine receptor type 1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXC-R1, CXCR-1, CXCR1, High affinity interleukin-8 receptor A, IL-8 receptor type 1, IL-8R A, IL8R1, IL8RA, IL8RBA, C-C |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CXCR1 |
| Short name: |
CXCR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-X-C motif) receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-C and C-C-CKR-1 and CD128 and CD181 and CDw128a and CKR-1 and CMKAR1 and IL8R1 and IL8RA and IL8RBA, CXCR1 and IDBG-80821 and ENSG00000163464 and 3577, Cxcr1 and IDBG-166431 and ENSMUSG00000048480 and 227288, Plasma membranes, interleukin-8 binding, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0004918 and interleukin-8 receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019959 and interleukin-8 binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0038112 and interleukin-8-mediated signaling pathway and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004918 : interleukin-8 receptor activity, this GO :0004918 : interleukin-8 receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0019959 : interleukin-8 binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0019959 : interleukin-8 binding, chemokine (C-X-C motif) receptor 1 |
| Identity: |
6026 |
| Gene: |
CXCR1 |
More about : CXCR1 |
| Long gene name: |
C-X-C motif chemokine receptor 1 |
| Synonyms gene: |
CMKAR1 IL8RA |
| Synonyms gene name: |
alpha chemokine (C-X-C motif) receptor 1 , interleukin 8 receptor |
| Synonyms: |
CKR-1 CDw128a CD181 |
| Locus: |
2q35 |
| Discovery year: |
1992-11-09 |
| GenBank acession: |
U11870 |
| Entrez gene record: |
3577 |
| Pubmed identfication: |
1303245 1427896 |
| RefSeq identity: |
NM_000634 |
| Classification: |
CD molecules C-X-C motif chemokine receptors Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133108 |