| Long name: |
SP1 Primary Polyclonal Antibody |
| Also known as: |
SP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SP1 |
| Specificity: |
This is a highly specific antibody against SP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
700-750/785 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSFP1/SP1 |
| Gene ID number: |
6667 |
| Swiss Prot: |
P08047 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds also the PDGFR-alpha G-box promoter, Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, Highly regulated by post-translational modifications (phosphorylations, Implicated in chromatin remodeling, In complex with ATF7IP, Isoform 3 is a stronger activator of transcription than isoform 1, May have a role in modulating the cellular response to DNA damage, Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter, Plays an essential role in the regulation of FE65 gene expression, Positively regulates the transcription of the core clock component ARNTL/BMAL1, apoptosis, differentiation and immune responses, glycosylation and acetylation), maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression, proteolytic cleavage, sumoylation, Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
SP1, TSFP1, Transcription factor Sp1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SP1 |
| Short name: |
SP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11205 |
| Gene: |
SP1 |
More about : SP1 |
| Long gene name: |
Sp1 transcription factor |
| Synonyms name: |
specificity protein 1 |
| Locus: |
12q13, 13 |
| Discovery year: |
1991-06-04 |
| GenBank acession: |
J03133 |
| Entrez gene record: |
6667 |
| Pubmed identfication: |
1662663 |
| Classification: |
Sp transcription factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000170047 |