| Long name: |
FITC Conjugated, MCKD2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MCKD2/UMOD |
| Specificity: |
This is a highly specific antibody against MCKD2/UMOD |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
120-170/640 |
| Subcellular location: |
Cell membrane, Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse MCKD2 |
| Gene ID number: |
22242 |
| Swiss Prot: |
Q91X17 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Facilitates neutrophil migration across renal epithelial (By similarity), IL-2) and TNF, Into the urine, May serve as a receptor for binding and endocytosis for cytokines (IL-1, Uromodulin, may contribute to colloid osmotic pressure, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals, retards passage of positively charged electrolytes, secreted form: Secreted into urine after proteolytically cleaveage, where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability, Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ADMCKD2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MCKD2 Conjugated |
| Short name: |
FITC Conjugated, MCKD2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, MCKD2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6942 |
| Gene: |
MCKD2 |
More about : MCKD2 |
| Long gene name: |
medullary cystic kidney disease 2 (autosomal dominant) |
| Locus: |
16p12 |
| Discovery year: |
1999-06-02 |
| Pubmed identfication: |
10330352 |