| Long name: |
MCKD2 Primary Polyclonal Antibody |
| Also known as: |
MCKD2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MCKD2/UMOD |
| Specificity: |
This is a highly specific antibody against MCKD2/UMOD |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
120-170/640 |
| Subcellular location: |
Cell membrane, Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse MCKD2 |
| Gene ID number: |
22242 |
| Swiss Prot: |
Q91X17 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Facilitates neutrophil migration across renal epithelial (By similarity), IL-2) and TNF, Into the urine, May serve as a receptor for binding and endocytosis for cytokines (IL-1, Uromodulin, may contribute to colloid osmotic pressure, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals, retards passage of positively charged electrolytes, secreted form: Secreted into urine after proteolytically cleaveage, where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability, Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Tamm-Horsfall urinary glycoprotein, Umod, Urehd1, Uromodulin, urehr4, THP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MCKD2 |
| Short name: |
MCKD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MCKD2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6942 |
| Gene: |
MCKD2 |
More about : MCKD2 |
| Long gene name: |
medullary cystic kidney disease 2 (autosomal dominant) |
| Synonyms: |
ADMCKD2 |
| Locus: |
16p12 |
| Discovery year: |
1999-06-02 |
| Pubmed identfication: |
10330352 |