| Long name: |
FITC Conjugated, TARDBP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TARDBP |
| Specificity: |
This is a highly specific antibody against TARDBP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
120-170/414 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human TDP-43 |
| Gene ID number: |
23435 |
| Swiss Prot: |
Q13148 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat, Involved in the regulation of CFTR splicing, It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon, May also be involved in microRNA biogenesis, Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR, The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis, apoptosis and cell division, DNA and RNA-binding protein which regulates transcription and splicing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
TDP-43 ALS10 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TARDBP Conjugated |
| Short name: |
FITC Conjugated, TARDBP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TARDBP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11571 |
| Gene: |
TARDBP |
More about : TARDBP |
| Long gene name: |
TAR DNA binding protein |
| Locus: |
1p36, 22 |
| Discovery year: |
2000-01-28 |
| GenBank acession: |
U23731 |
| Entrez gene record: |
23435 |
| Pubmed identfication: |
7745706 |
| RefSeq identity: |
NM_007375 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000002120 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_659 |