| Long name: |
Biotin Conjugated, TARDBP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TARDBP |
| Specificity: |
This is a highly specific antibody against TARDBP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
120-170/414 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human TDP-43 |
| Gene ID number: |
23435 |
| Swiss Prot: |
Q13148 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat, Involved in the regulation of CFTR splicing, It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon, May also be involved in microRNA biogenesis, Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR, The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis, apoptosis and cell division, DNA and RNA-binding protein which regulates transcription and splicing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
TDP-43 ALS10 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TARDBP Conjugated |
| Short name: |
Conjugated, TARDBP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TARDBP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11571 |
| Gene: |
TARDBP |
More about : TARDBP |
| Long gene name: |
TAR DNA binding protein |
| Locus: |
1p36, 22 |
| Discovery year: |
2000-01-28 |
| GenBank acession: |
U23731 |
| Entrez gene record: |
23435 |
| Pubmed identfication: |
7745706 |
| RefSeq identity: |
NM_007375 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000002120 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_659 |