| Long name: |
Kisspeptin Primary Polyclonal Antibody |
| Also known as: |
Kisspeptin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Kisspeptin |
| Specificity: |
This antibody detects Kisspeptin-10 region of Kisspeptin, This is a highly specific antibody against Kisspeptin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
112-121/138 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Kiss-1 |
| Gene ID number: |
3814 |
| Swiss Prot: |
Q15726 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activation of the receptor inhibits cell proliferation and cell migration, Generates a C-terminally amidated peptide, Kp-1, Kp-1 is a decapeptide derived from the primary translation product, Kp-1 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself, May regulate events downstream of cell-matrix adhesion, The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood, The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts, isolated in conditioned medium of first trimester trophoblast, key characteristics of tumor metastasis, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54, perhaps involving cytoskeletal reorganization, Metastasis suppressor protein in malignant melanomas and in some breast cancers |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
KISS1, KiSS-1, Kisspeptin-1, Metastasis-suppressor KiSS-1, PP598, HH13 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Kisspeptin |
| Short name: |
Kisspeptin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Kisspeptin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6341 |
| Gene: |
KISS1 |
More about : KISS1 |
| Long gene name: |
KiSS-1 metastasis-suppressor |
| Synonyms name: |
prepro-kisspeptin kisspeptin |
| Locus: |
1q32, 1 |
| Discovery year: |
1998-05-18 |
| GenBank acession: |
U43527 |
| Entrez gene record: |
3814 |
| Pubmed identfication: |
9192814 9806840 |
| RefSeq identity: |
NM_002256 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000036060 |