| Long name: |
ALEXA FLUOR 350 Conjugated, CD272 Polyclonal Antibody |
| Also known as: |
Anti-CD272 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD272 |
| Specificity: |
This is a highly specific antibody against CD272 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
239-289/289 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator |
| Gene ID Number: |
151888 |
| Swiss Prot: |
Q7Z6A9 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
B7x, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1), BTLA is not expressed by naive T cells, BTLA-deficient T cells show increased proliferation, Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, Thus, a peripheral homolog of B7, an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis, and attenuates production of interleukin 2 (IL-2), but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells, is a ligand of BTLA, B and T lymphocyte attenuator (BTLA) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
BTLA1 CD272 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
CD272 |
| Short name: |
CD272 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, CD272 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21087 |
| Gene: |
BTLA |
More about : BTLA |
| Long gene name: |
B and T lymphocyte associated |
| Locus: |
3q13, 2 |
| Discovery year: |
2003-08-20 |
| GenBank acession: |
AY293286 |
| Entrez gene record: |
151888 |
| Pubmed identfication: |
12796776 |
| RefSeq identity: |
NM_181780 |
| Classification: |
Immunoglobulin like domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000159255 |