| Long name: |
ADRA1A Primary Polyclonal Antibody |
| Also known as: |
ADRA1A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ADRA1A |
| Specificity: |
This is a highly specific antibody against ADRA1A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
206-256/466 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Alpha-1A adrenergic receptor |
| Gene ID number: |
148 |
| Swiss Prot: |
P35348 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Its effect is mediated by G(q) and G(11) proteins, Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes, This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ADRA1A, ADRA1L1, ALPHA1AAR, Alpha-1A adrenergic receptor, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c, ADRA1C |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADRA1A |
| Short name: |
ADRA1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
adrenoceptor a 1A (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADRA1A and IDBG-13362 and ENSG00000120907 and 148, ADRA1A and IDBG-635639 and ENSBTAG00000031632 and 282134, ADRA1C and ADRA1L1 and ALPHA1AAR, Adra1a and IDBG-175481 and ENSMUSG00000045875 and 11549, GABAergic and biological process this GO :0032230 and positive regulation of synaptic transmission, GABAergic and biological process this GO :0035024 and negative regulation of Rho protein signal transduction and biological process this GO :0035265 and organ growth and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042493 and response to drug and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045760 and positive regulation of action potential and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045987 and positive regulation of smooth muscle contraction and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0055117 and regulation of cardiac muscle contraction and biological process this GO :0060073 and micturition and biological process this GO :0060402 and calcium ion transport into cytosol and biological process this GO :0060452 and positive regulation of cardiac muscle contraction and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071875 and adrenergic receptor signaling pathway and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :0097195 and pilomotor reflex and biological process, nuclei, protein heterodimerization activity, this GO :0001985 and negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure and biological process this GO :0001994 and norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure and biological process this GO :0001996 and positive regulation of heart rate by epinephrine-norepinephrine and biological process this GO :0001997 and positive regulation of the force of heart contraction by epinephrine-norepinephrine and biological process this GO :0003084 and positive regulation of systemic arterial blood pressure and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004937 and alpha1-adrenergic receptor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006939 and smooth muscle contraction and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007512 and adult heart development and biological process this GO :0007568 and aging and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009725 and response to hormone and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016049 and cell growth and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0030018 and Z disc and cellular component this GO :0030315 and T-tubule and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032229 and negative regulation of synaptic transmission, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004937 : alpha1-adrenergic receptor activity and also this GO :0046982 : protein heterodimerization activity, this GO :0004937 : alpha1-adrenergic receptor activity, this GO :0046982 : protein heterodimerization activity, adrenoceptor alpha 1A |
| Identity: |
277 |
| Gene: |
ADRA1A |
More about : ADRA1A |
| Long gene name: |
adrenoceptor alpha 1A |
| Synonyms gene: |
ADRA1C |
| Synonyms gene name: |
adrenergic, alpha-1A-, receptor |
| Synonyms: |
ADRA1L1 |
| Locus: |
8p21, 2 |
| Discovery year: |
1991-08-19 |
| GenBank acession: |
L31774 |
| Entrez gene record: |
148 |
| RefSeq identity: |
NM_033303 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000099459 |