| Long name: |
ALEXA FLUOR 488 Conjugated, CDKN1C Polyclonal Antibody |
| Also known as: |
Anti-CDKN1C PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CDKN1C |
| Specificity: |
This is a highly specific antibody against CDKN1C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
280-330/343 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from rat Cdkn1c |
| Gene ID Number: |
246060 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, Oct 2010], The encoded protein is a tight-binding, Three transcript variants encoding two different isoforms have been found for this gene, [provided by RefSeq, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation, suggesting that this gene is a tumor suppressor candidate, with preferential expression of the maternal allele, This gene is imprinted |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
P57 KIP2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CDKN1C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CDKN1C |
| Short name: |
CDKN1C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Kip2) (Antibody to), cyclin-dependent kinase inhibitor 1C (p57 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BWCR and BWS and KIP2 and p57 and p57Kip2 and WBS, CDKN1C and IDBG-23324 and ENSG00000129757 and 1028, CDKN1C and IDBG-645186 and ENSBTAG00000031184 and 510972, Cdkn1c and IDBG-212725 and ENSMUSG00000037664 and 12577, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0055123 and digestive system development and biological process this GO :0060065 and uterus development and biological process this GO :0060669 and embryonic placenta morphogenesis and biological process this GO :0071514 and genetic imprinting and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process, Kip2), nuclei, protein binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000080 and mitotic G1 phase and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001501 and skeletal system development and biological process this GO :0001822 and kidney development and biological process this GO :0001890 and placenta development and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0007568 and aging and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030511 and positive regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0033673 and negative regulation of kinase activity and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042551 and neuron maturation and biological process this GO :0043010 and camera-type eye development and biological process this GO :0045892 and negative regulation of transcription, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cyclin-dependent kinase inhibitor 1C (p57 |
| Identity: |
1786 |
| Gene: |
CDKN1C |
More about : CDKN1C |
| Long gene name: |
cyclin dependent kinase inhibitor 1C |
| Synonyms gene: |
BWCR BWS |
| Synonyms gene name: |
Beckwith-Wiedemann syndrome cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| Locus: |
11p15, 4 |
| Discovery year: |
1995-09-14 |
| GenBank acession: |
D64137 |
| Entrez gene record: |
1028 |
| Pubmed identfication: |
7729684 |
| RefSeq identity: |
NM_000076 |
| Havana BLAST/BLAT: |
OTTHUMG00000010040 |
| Locus Specific Databases: |
LRG_533 |