| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDKN1C |
| Specificity: |
This antibody reacts specifically with CDKN1C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from rat Cdkn1c |
| Gene ID: |
246060 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, Oct 2010], The encoded protein is a tight-binding, Three transcript variants encoding two different isoforms have been found for this gene, [provided by RefSeq, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation, suggesting that this gene is a tumor suppressor candidate, with preferential expression of the maternal allele, This gene is imprinted |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
P57 KIP2 |
| Also known as: |
CDKN1C Polyclonal Antibody |
| Other name: |
Anti-CDKN1C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDKN1C |
| Short name: |
Anti-CDKN1C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, Kip2) (polyclonal), antibody to-cyclin-dependent kinase inhibitor 1C (p57 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BWCR and BWS and KIP2 and p57 and p57Kip2 and WBS, CDKN1C and IDBG-23324 and ENSG00000129757 and 1028, CDKN1C and IDBG-645186 and ENSBTAG00000031184 and 510972, Cdkn1c and IDBG-212725 and ENSMUSG00000037664 and 12577, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0055123 and digestive system development and biological process this GO :0060065 and uterus development and biological process this GO :0060669 and embryonic placenta morphogenesis and biological process this GO :0071514 and genetic imprinting and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process, Kip2), nuclei, protein binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000080 and mitotic G1 phase and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001501 and skeletal system development and biological process this GO :0001822 and kidney development and biological process this GO :0001890 and placenta development and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0007568 and aging and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030511 and positive regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0033673 and negative regulation of kinase activity and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042551 and neuron maturation and biological process this GO :0043010 and camera-type eye development and biological process this GO :0045892 and negative regulation of transcription, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cyclin-dependent kinase inhibitor 1C (p57 |
| Identity: |
1786 |
| Gene: |
CDKN1C |
More about : CDKN1C |
| Long gene name: |
cyclin dependent kinase inhibitor 1C |
| Synonyms gene: |
BWCR BWS |
| Synonyms gene name: |
Beckwith-Wiedemann syndrome cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| Locus: |
11p15, 4 |
| Discovery year: |
1995-09-14 |
| GenBank acession: |
D64137 |
| Entrez gene record: |
1028 |
| Pubmed identfication: |
7729684 |
| RefSeq identity: |
NM_000076 |
| Havana BLAST/BLAT: |
OTTHUMG00000010040 |
| Locus Specific Databases: |
LRG_533 |